| Biography | |
|---|---|
 Prof. Md Ahsan Habib University of Dhaka, Bangladesh |
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| Title: Mass spectrometry in chemical analysis | |
| Abstract: Mass spectrometry (MS) is considered as a ‘gold standard’ in the field of analytical science because it provides direct molecular structural information of relevant analyte molecules. Therefore, MS technique has been extensively used in the branches of chemistry along with in agriculture, food science, proteomics, metabolomics, genomics, lipidomics etc. Recent research on “MS imaging for biological samples” exhibited as a promising diagnostic tool for cancer diagnosis. Almost all types of compounds exist as neutral form except proteins, peptides, nucleic acids which exist inherently ionic in nature. In MS, an ionization source which is considered as the heart of the MS, has been used to ionize the neutral molecules. Performance of MS in terms of quantification depends on the efficiency of the ion source. Therefore development an efficient ion source is very much needed. Traditional ion sources like chemical ionization (CI), electron ionization (EI), electrospray ionization (ESI) need high vacuum system which make the MS heavier and bulky where miniature MS is very much needed for practical applications. Development of ambient ion source would be the choice to fabricate miniature MS. Attempts have been paid to develop ambient ion source for analysis of various compounds with better limit of detection. Further attempt has been taken to develop new desorption method for non-volatile compounds. This is because in MS, the analyte compounds must be released in gas phase and then ionizes by a suitable ion source. There are two representative methods for gasification of condensed samples, i.e., ablation and desorption. Flash heating/rapid cooling, solid/solid friction, liquid/solid friction etc have been developed as desorption methods for non-volatile compounds. All the methods are concerned with the surface and interface phenomena. Mechanism of ion formation and better ionization efficiency of new ion sources and concept of how to desorb less-volatility compounds from the surface will be discussed. Keywords-Ambient Ionization Source, Ambient Mass Spectrometry, Miniature Mass Spectrometry, Desorption Methods for Non-Volatile Compounds | |
| Biography: Md Ahsan Habib is currently working as a Full Professor in the Department of Chemistry (Analytical and Environmental Section), University of Dhaka (Bangladesh) from where he completed his BSc (Hons) in 1991 and MSc in 1993. Dr. Habib completed his MPhil from the Department of Chemistry, Bangladesh University of Engineering and Technology in 2001. In 2004, Dr. Ahsan Habib obtained his PhD from the Department of Chemistry, Saga University (Japan) and he completed four post doctoral researches along with JSPS Invitation fellowship at five Japanese Universities in various fields in Chemistry. Prof. Habib has also worked as a visiting professor at Ningbo University and Guangzhou Institute of Geochemistry (GIG), China. Dr. Habib published 45 papers in various international journals and delivered talk at many international conferences. | |
